It curses the body.
First as to the body. One would
suppose, from the marred and scarred, and sometimes
awfully disfigured forms and faces of men who have
indulged in intoxicating drinks, which are to be seen
everywhere and among all classes of society, that
there would be no need of other testimony to show
that alcohol is an enemy to the body. And yet,
strange to say, men of good sense, clear judgment
and quick perception in all moral questions and in
the general affairs of life, are often so blind, or
infatuated here, as to affirm that this substance,
alcohol, which they use under the various forms of
wine, brandy, whisky, gin, ale or beer, is not only
harmless, when taken in moderation—each
being his own judge as to what “moderation”
means—but actually useful and nutritious!
Until within the last fifteen or twenty
years, a large proportion of the medical profession
not only favored this view, but made constant prescription
of alcohol in one form or another, the sad results
of which too often made their appearance in exacerbations
of disease, or in the formation of intemperate habits
among their patients. Since then, the chemist
and the physiologist have subjected alcohol to the
most rigid tests, carried on often for years, and
with a faithfulness that could not be satisfied with
guess work, or inference, or hasty conclusion.
ALCOHOL NOT A FOOD AND OF DOUBTFUL USE AS A MEDICINE.
As a result of these carefully-conducted
and long-continued examinations and experiments, the
medical profession stands to-day almost as a unit
against alcohol; and makes solemn public declaration
to the people that it “is not shown to have
a definite food value by any of the usual methods
of chemical analysis or physiological investigations;”
and that as a medicine its range is very limited,
admitting often of a substitute, and that it should
never be taken unless prescribed by a physician.
Reports of these investigations to
which we have referred have appeared, from time to
time, in the medical journals of Europe and America,
and their results are now embodied in many of the
standard and most reliable treatises and text-books
of the medical profession.
In this chapter we shall endeavor
to give our readers a description of the changes and
deteriorations which take place in the blood, nerves,
membranes, tissues and organs, in consequence of the
continued introduction of alcohol into the human body;
and in doing so, we shall quote freely from medical
writers, in order that our readers may have the testimony
before them in its directest form, and so be able to
judge for themselves as to its value.
DIGESTION.
And here, in order to give those who
are not familiar with, the process of digestion, a
clear idea of that important operation, and the effect
produced when alcohol is taken with food, we quote
from the lecture of an English physician, Dr. Henry
Monroe, on “The Physiological Action of Alcohol.”
He says:
“Every kind of substance employed
by man as food consists of sugar, starch, oil and
glutinous matters, mingled together in various proportions;
these are designed for the support of the animal frame.
The glutinous principles of food—fibrine,
albumen and casein—are employed
to build up the structure; while the oil, starch
and sugar are chiefly used to generate heat
in the body.
“The first step of the digestive
process is the breaking up of the food in the mouth
by means of the jaws and teeth. On this being
done, the saliva, a viscid liquor, is poured into
the mouth from the salivary glands, and as it mixes
with the food, it performs a very important part in
the operation of digestion, rendering the starch of
the food soluble, and gradually changing it into a
sort of sugar, after which the other principles become
more miscible with it. Nearly a pint of saliva
is furnished every twenty-four hours for the use of
an adult. When the food has been masticated and
mixed with the saliva, it is then passed into the
stomach, where it is acted upon by a juice secreted
by the filaments of that organ, and poured into the
stomach in large quantities whenever food comes in
contact with its mucous coats. It consists of
a dilute acid known to the chemists as hydrochloric
acid, composed of hydrogen and chlorine, united together
in certain definite proportions. The gastric
juice contains, also, a peculiar organic-ferment or
decomposing substance, containing nitrogen—something
of the nature of yeast—termed pepsine,
which is easily soluble in the acid just named.
That gastric juice acts as a simple chemical solvent,
is proved by the fact that, after death, it has been
known to dissolve the stomach itself.”
ALCOHOL RETARDS DIGESTION.
“It is an error to suppose that,
after a good dinner, a glass of spirits or beer assists
digestion; or that any liquor containing alcohol—even
bitter beer—can in any way assist digestion.
Mix some bread and meat with gastric juice; place
them in a phial, and keep that phial in a sand-bath
at the slow heat of 98 degrees, occasionally shaking
briskly the contents to imitate the motion of the
stomach; you will find, after six or eight hours,
the whole contents blended into one pultaceous mass.
If to another phial of food and gastric juice, treated
in the same way, I add a glass of pale ale or a quantity
of alcohol, at the end of seven or eight hours, or
even some days, the food is scarcely acted upon at
all. This is a fact; and if you are led to ask
why, I answer, because alcohol has the peculiar power
of chemically affecting or decomposing the gastric
juice by precipitating one of its principal constituents,
viz., pepsine, rendering its solvent properties
much less efficacious. Hence alcohol can not
be considered either as food or as a solvent for food.
Not as the latter certainly, for it refuses to act
with the gastric juice.
“‘It is a remarkable fact,’
says Dr. Dundas Thompson, ’that alcohol, when
added to the digestive fluid, produces a white precipitate,
so that the fluid is no longer capable of digesting
animal or vegetable matter.’ ‘The
use of alcoholic stimulants,’ say Drs. Todd and
Bowman, ’retards digestion by coagulating the
pepsine, an essential element of the gastric juice,
and thereby interfering with its action. Were
it not that wine and spirits are rapidly absorbed,
the introduction of these into the stomach, in any
quantity, would be a complete bar to the digestion
of food, as the pepsine would be precipitated from
the solution as quickly as it was formed by the stomach.’
Spirit, in any quantity, as a dietary adjunct, is
pernicious on account of its antiseptic qualities,
which resist the digestion of food by the absorption
of water from its particles, in direct antagonism
to chemical operation.”
ITS EFFECT ON THE BLOOD.
Dr. Richardson, in his lectures on
alcohol, given both in England and America, speaking
of the action of this substance on the blood after
passing from the stomach, says:
“Suppose, then, a certain measure
of alcohol be taken into the stomach, it will be absorbed
there, but, previous to absorption, it will have to
undergo a proper degree of dilution with water, for
there is this peculiarity respecting alcohol when
it is separated by an animal membrane from a watery
fluid like the blood, that it will not pass through
the membrane until it has become charged, to a given
point of dilution, with water. It is itself,
in fact, so greedy for water, it will pick it up
from watery textures, and deprive them of it until,
by its saturation, its power of reception is exhausted,
after which it will diffuse into the current of circulating
fluid.”
It is this power of absorbing water
from every texture with which alcoholic spirits comes
in contact, that creates the burning thirst of those
who freely indulge in its use. Its effect, when
it reaches the circulation, is thus described by Dr.
Richardson:
“As it passes through the circulation
of the lungs it is exposed to the air, and some little
of it, raised into vapor by the natural heat, is thrown
off in expiration. If the quantity of it be large,
this loss may be considerable, and the odor of the
spirit may be detected in the expired breath.
If the quantity be small, the loss will be comparatively
little, as the spirit will be held in solution by the
water in the blood. After it has passed through
the lungs, and has been driven by the left heart over
the arterial circuit, it passes into what is called
the minute circulation, or the structural circulation
of the organism. The arteries here extend into
very small vessels, which are called arterioles, and
from these infinitely small vessels spring the equally
minute radicals or roots of the veins, which are ultimately
to become the great rivers bearing the blood back
to the heart. In its passage through this minute
circulation the alcohol finds its way to every organ.
To this brain, to these muscles, to these secreting
or excreting organs, nay, even into this bony structure
itself, it moves with the blood. In some of these
parts which are not excreting, it remains for a time
diffused, and in those parts where there is a large
percentage of water, it remains longer than in other
parts. From some organs which have an open tube
for conveying fluids away, as the liver and kidneys,
it is thrown out or eliminated, and in this way a portion
of it is ultimately removed from the body. The
rest passing round and round with the circulation,
is probably decomposed and carried off in new forms
of matter.
“When we know the course which
the alcohol takes in its passage through the body,
from the period of its absorption to that of its elimination,
we are the better able to judge what physical changes
it induces in the different organs and structures
with which it comes in contact. It first reaches
the blood; but, as a rule, the quantity of it that
enters is insufficient to produce any material effect
on that fluid. If, however, the dose taken be
poisonous or semi-poisonous, then even the blood,
rich as it is in water—and it contains seven
hundred and ninety parts in a thousand—is
affected. The alcohol is diffused through this
water, and there it comes in contact with the other
constituent parts, with the fibrine, that plastic
substance which, when blood is drawn, clots and coagulates,
and which is present in the proportion of from two
to three parts in a thousand; with the albumen which
exists in the proportion of seventy parts; with the
salts which yield about ten parts; with the fatty
matters; and lastly, with those minute, round bodies
which float in myriads in the blood (which were discovered
by the Dutch philosopher, Leuwenhock, as one of the
first results of microscopical observation, about
the middle of the seventeenth century), and which are
called the blood globules or corpuscles. These
last-named bodies are, in fact, cells; their discs,
when natural, have a smooth outline, they are depressed
in the centre, and they are red in color; the color
of the blood being derived from them. We have
discovered in recent years that there exist other
corpuscles or cells in the blood in much smaller quantity,
which are called white cells, and these different cells
float in the blood-stream within the vessels.
The red take the centre of the stream; the white lie
externally near the sides of the vessels, moving less
quickly. Our business is mainly with the red corpuscles.
They perform the most important functions in the economy;
they absorb, in great part, the oxygen which we inhale
in breathing, and carry it to the extreme tissues
of the body; they absorb, in great part, the carbonic
acid gas which is produced in the combustion of the
body in the extreme tissues, and bring that gas back
to the lungs to be exchanged for oxygen there; in
short, they are the vital instruments of the circulation.
“With all these parts of the
blood, with the water, fibrine, albumen, salts, fatty
matter and corpuscles, the alcohol comes in contact
when it enters the blood, and, if it be in sufficient
quantity, it produces disturbing action. I have
watched this disturbance very carefully on the blood
corpuscles; for, in some animals we can see these floating
along during life, and we can also observe them from
men who are under the effects of alcohol, by removing
a speck of blood, and examining it with the microscope.
The action of the alcohol, when it is observable, is
varied. It may cause the corpuscles to run too
closely together, and to adhere in rolls; it may modify
their outline, making the clear-defined, smooth, outer
edge irregular or crenate, or even starlike; it may
change the round corpuscle into the oval form, or,
in very extreme cases, it may produce what I may call
a truncated form of corpuscles, in which the change
is so great that if we did not trace it through all
its stages, we should be puzzled to know whether the
object looked at were indeed a blood-cell. All
these changes are due to the action of the spirit upon
the water contained in the corpuscles; upon the capacity
of the spirit to extract water from them. During
every stage of modification of corpuscles thus described,
their function to absorb and fix gases is impaired,
and when the aggregation of the cells, in masses, is
great, other difficulties arise, for the cells, united
together, pass less easily than they should through
the minute vessels of the lungs and of the general
circulation, and impede the current, by which local
injury is produced.
“A further action upon the blood,
instituted by alcohol in excess, is upon the fibrine
or the plastic colloidal matter. On this the spirit
may act in two different ways, according to the degree
in which it affects the water that holds the fibrine
in solution. It may fix the water with the fibrine,
and thus destroy the power of coagulation; or it may
extract the water so determinately as to produce coagulation.”
ON THE MINUTE CIRCULATION.
The doctor then goes on to describe
the minute circulation through which the constructive
material in the blood is distributed to every part
of the body. “From this distribution of
blood in these minute vessels,” he says, “the
structure of organs derive their constituent parts;
through these vessels brain matter, muscle, gland,
membrane, are given out from the blood by a refined
process of selection of material, which, up to this
time, is only so far understood as to enable us to
say that it exists. The minute and intermediate
vessels are more intimately connected than any other
part with the construction and with the function of
the living matter of which the body is composed.
Think you that this mechanism is left uncontrolled?
No; the vessels, small as they are, are under distinct
control. Infinitely refined in structure, they
nevertheless have the power of contraction and dilatation,
which power is governed by nervous action of a special
kind.”
Now, there are certain chemical agents,
which, by their action on the nerves, have the power
to paralyze and relax these minute blood-vessels,
at their extreme points. “The whole series
of nitrates,” says Dr. Richardson, “possess
this power; ether possesses it; but the great point
I wish to bring forth is, that the substance we are
specially dealing with, alcohol, possesses the self-same
power. By this influence it produces all those
peculiar effects which in every-day life are so frequently
illustrated.”
PARALYZES THE MINUTE BLOOD-VESSELS.
It paralyzes the minute blood-vessels,
and allows them to become dilated with the flowing
blood.
“If you attend a large dinner
party, you will observe, after the first few courses,
when the wine is beginning to circulate, a progressive
change in some of those about you who have taken wine.
The face begins to get flushed, the eye brightens,
and the murmur of conversation becomes loud.
What is the reason of that flushing of the countenance?
It is the same as the flush from blushing, or from
the reaction of cold, or from the nitrite of amyl.
It is the dilatation of vessels following upon the
reduction of nervous control, which reduction has been
induced by the alcohol. In a word, the first
stage, the stage of vascular excitement from alcohol,
has been established.”
HEART DISTURBANCE.
“The action of the alcohol extending
so far does not stop there. With the disturbance
of power in the extreme vessels, more disturbance is
set up in other organs, and the first organ that shares
in it is the heart. With each beat of the heart
a certain degree of resistance is offered by the vessels
when their nervous supply is perfect, and the stroke
of the heart is moderated in respect both to tension
and to time. But when the vessels are rendered
relaxed, the resistance is removed, the heart begins
to run quicker, like a watch from which the pallets
have been removed, and the heart-stroke, losing nothing
in force, is greatly increased in frequency, with
a weakened recoil stroke. It is easy to account,
in this manner, for the quickened heart and pulse which
accompany the first stage of deranged action from alcohol,
and you will be interested to know to what extent
this increase of vascular action proceeds. The
information on this subject is exceedingly curious
and important.”
* * * *
“The stage of primary excitement
of the circulation thus induced lasts for a considerable
time, but at length the heart flags from its overaction,
and requires the stimulus of more spirit to carry it
on in its work. Let us take what we may call
a moderate amount of alcohol, say two ounces by volume,
in form of wine, or beer, or spirits. What is
called strong sherry or port may contain as much as
twenty-five per cent. by volume. Brandy over
fifty; gin, thirty-eight; rum, forty-eight; whisky,
forty-three; vin ordeinaire, eight; strong ale, fourteen;
champagne, ten to eleven; it matters not which, if
the quantity of alcohol be regulated by the amount
present in the liquor imbibed. When we reach
the two ounces, a distinct physiological effect follows,
leading on to that first stage of excitement with which
we are now conversant. The reception of the spirit
arrested at this point, there need be no important
mischief done to the organism; but if the quantity
imbibed be increased, further changes quickly occur.
We have seen that all the organs of the body are built
upon the vascular structures, and therefore it follows
that a prolonged paralysis of the minute circulation
must of necessity lead to disturbance in other organs
than the heart.”
OTHER ORGANS INVOLVED.
“By common observation, the
flush seen on the cheek during the first stage of
alcoholic excitation, is presumed to extend merely
to the parts actually exposed to view. It cannot,
however, be too forcibly impressed that the condition
is universal in the body. If the lungs could be
seen, they, too, would be found with their vessels
injected; if the brain and spinal cord could be laid
open to view, they would be discovered in the same
condition; if the stomach, the liver, the spleen, the
kidneys or any other vascular organs or parts could
be exposed, the vascular engorgement would be equally
manifest. In the lower animals, I have been able
to witness this extreme vascular condition in the lungs,
and there are here presented to you two drawings from
nature, showing, one the lungs in a natural state
of an animal killed by a sudden blow, the other the
lungs of an animal killed equally suddenly, but at
a time when it was under the influence of alcohol.
You will see, as if you were looking at the structures
themselves, how different they are in respect to the
blood which they contained, how intensely charged with
blood is the lung in which the vessels had been paralyzed
by the alcoholic Spirit.”
EFFECT ON THE BRAIN.
“I once had the unusual, though
unhappy, opportunity of observing the same phenomenon
in the brain structure of a man, who, in a paroxysm
of alcoholic excitement, decapitated himself under
the wheel of a railway carriage, and whose brain was
instantaneously evolved from the skull by the crash.
The brain itself, entire, was before me within three
minutes after the death. It exhaled the odor
of spirit most distinctly, and its membranes and minute
structures were vascular in the extreme. It looked
as if it had been recently injected with vermilion.
The white matter of the cerebrum, studded with red
points, could scarcely be distinguished, when it was
incised, by its natural whiteness; and the pia-mater,
or internal vascular membrane covering the brain,
resembled a delicate web of coagulated red blood,
so tensely were its fine vessels engorged.
“I should add that this condition
extended through both the larger and the smaller brain,
the cerebrum and cerebellum, but was not so marked
in the medulla or commencing portion of the spinal
cord.”
THE SPINAL CORD AND NERVES.
“The action of alcohol continued
beyond the first stage, the function of the spinal
cord is influenced. Through this part of the nervous
system we are accustomed, in health, to perform automatic
acts of a mechanical kind, which proceed systematically
even when we are thinking or speaking on other subjects.
Thus a skilled workman will continue his mechanical
work perfectly, while his mind is bent on some other
subject; and thus we all perform various acts in a
purely automatic way, without calling in the aid of
the higher centres, except something more than ordinary
occurs to demand their service, upon which we think
before we perform. Under alcohol, as the spinal
centres become influenced, these pure automatic acts
cease to be correctly carried on. That the hand
may reach any object, or the foot be correctly planted,
the higher intellectual centre must be invoked to
make the proceeding secure. There follows quickly
upon this a deficient power of co-ordination of muscular
movement. The nervous control of certain of the
muscles is lost, and the nervous stimulus is more
or less enfeebled. The muscles of the lower lip
in the human subject usually fail first of all, then
the muscles of the lower limbs, and it is worthy of
remark that the extensor muscles give way earlier
than the flexors. The muscles themselves, by this
time, are also failing in power; they respond more
feebly than is natural to the nervous stimulus; they,
too, are coming under the depressing influence of
the paralyzing agent, their structure is temporarily
deranged, and their contractile power reduced.
“This modification of the animal
functions under alcohol, marks the second degree of
its action. In young subjects, there is now, usually,
vomiting with faintness, followed by gradual relief
from the burden of the poison.”
[Illustration: AN UTTER WRECK.]
EFFECT ON THE BRAIN CENTRES.
“The alcoholic spirit carried
yet a further degree, the cerebral or brain centres
become influenced; they are reduced in power, and the
controlling influences of will and of judgment are
lost. As these centres are unbalanced and thrown
into chaos, the rational part of the nature of the
man gives way before the emotional, passional or organic
part. The reason is now off duty, or is fooling
with duty, and all the mere animal instincts and sentiments
are laid atrociously bare. The coward shows up
more craven, the braggart more boastful, the cruel
more merciless, the untruthful more false, the carnal
more degraded. ’In vino veritas’
expresses, even, indeed, to physiological accuracy,
the true condition. The reason, the emotions,
the instincts, are all in a state of carnival, and
in chaotic feebleness.
“Finally, the action of the
alcohol still extending, the superior brain centres
are overpowered; the senses are beclouded, the voluntary
muscular prostration is perfected, sensibility is lost,
and the body lies a mere log, dead by all but one-fourth,
on which alone its life hangs. The heart still
remains true to its duty, and while it just lives
it feeds the breathing power. And so the circulation
and the respiration, in the otherwise inert mass,
keeps the mass within the bare domain of life until
the poison begins to pass away and the nervous centres
to revive again. It is happy for the inebriate
that, as a rule, the brain fails so long before the
heart that he has neither the power nor the sense
to continue his process of destruction up to the act
of death of his circulation. Therefore he lives
to die another day.
* * *
*
“Such is an outline of the primary
action of alcohol on those who may be said to be unaccustomed
to it, or who have not yet fallen into a fixed habit
of taking it: For a long time the organism will
bear these perversions of its functions without apparent
injury, but if the experiment be repeated too often
and too long, if it be continued after the term of
life when the body is fully developed, when the elasticity
of the membranes and of the blood-vessels is lessened,
and when the tone of the muscular fibre is reduced,
then organic series of structural changes, so characteristic
of the persistent effects of spirit, become prominent
and permanent. Then the external surface becomes
darkened and congested, its vessels, in parts, visibly
large; the skin becomes blotched, the proverbial red
nose is defined, and those other striking vascular
changes which disfigure many who may probably be called
moderate alcoholics, are developed. These changes,
belonging, as they do, to external surfaces, come
under direct observation; they are accompanied with
certain other changes in the internal organs, which
we shall show to be more destructive still.”